BDBM50061117 6,6,9-Trimethyl-3-pentyl-6H-benzo[c]chromen-1-ol::6,6,9-Trimethyl-3-pentyl-6H-benzo[c]chromen-1-ol (Cannabinol)::6,6,9-Trimethyl-3-pentyl-6H-benzo[c]chromen-1-ol(Cannabinol)::CANNABINOL::CBN::CHEMBL74415

SMILES CCCCCc1cc(O)c-2c(OC(C)(C)c3ccc(C)cc-23)c1

InChI Key InChIKey=VBGLYOIFKLUMQG-UHFFFAOYSA-N

Data  21 KI  12 IC50  17 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50061117   

TargetCannabinoid receptor 2(Homo sapiens (Human))
Concordia University Wisconsin

Curated by ChEMBL
LigandPNGBDBM50061117(6,6,9-Trimethyl-3-pentyl-6H-benzo[c]chromen-1-ol |...)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]-CP55940 from recombinant human CB2 receptor expressed in Sf9 cell membranes co-expressing Galphai3beta1gamma2 measured after 90 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Concordia University Wisconsin

Curated by ChEMBL
LigandPNGBDBM50061117(6,6,9-Trimethyl-3-pentyl-6H-benzo[c]chromen-1-ol |...)
Affinity DataKi:  70nMAssay Description:Binding affinity to to CB2 receptor (unknown origin) expressed in CHO -k1 cells assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Concordia University Wisconsin

Curated by ChEMBL
LigandPNGBDBM50061117(6,6,9-Trimethyl-3-pentyl-6H-benzo[c]chromen-1-ol |...)
Affinity DataKi:  95nMAssay Description:Binding affinity towards cloned human cannabinoid receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Concordia University Wisconsin

Curated by ChEMBL
LigandPNGBDBM50061117(6,6,9-Trimethyl-3-pentyl-6H-benzo[c]chromen-1-ol |...)
Affinity DataKi:  96nMAssay Description:Binding affinity was determined for Cannabinoid receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Concordia University Wisconsin

Curated by ChEMBL
LigandPNGBDBM50061117(6,6,9-Trimethyl-3-pentyl-6H-benzo[c]chromen-1-ol |...)
Affinity DataKi:  126nMAssay Description:Binding affinity of compound towards Cannabinoid receptor 2 in african green monkey COS-7 cells transfected with cDNA of human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Concordia University Wisconsin

Curated by ChEMBL
LigandPNGBDBM50061117(6,6,9-Trimethyl-3-pentyl-6H-benzo[c]chromen-1-ol |...)
Affinity DataKi:  300nMAssay Description:Binding affinity to to CB2 receptor (unknown origin) expressed in AtT20 cells assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Concordia University Wisconsin

Curated by ChEMBL
LigandPNGBDBM50061117(6,6,9-Trimethyl-3-pentyl-6H-benzo[c]chromen-1-ol |...)
Affinity DataEC50:  261nMAssay Description:Effective concentration for inhibition of human Cannabinoid receptor 2-mediated adenylylcyclase using African green monkey (COS-7) cells transfected ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Concordia University Wisconsin

Curated by ChEMBL
LigandPNGBDBM50061117(6,6,9-Trimethyl-3-pentyl-6H-benzo[c]chromen-1-ol |...)
Affinity DataEC50:  60nMAssay Description:Displacement of 35S]GTPgammaS from human CB2 receptor transfected in CHO cells assessed as inhibition forskolin-stimulated cyclic AMP productionMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Concordia University Wisconsin

Curated by ChEMBL
LigandPNGBDBM50061117(6,6,9-Trimethyl-3-pentyl-6H-benzo[c]chromen-1-ol |...)
Affinity DataEC50:  73nMAssay Description:Displacement of 3H-CP-55940 from recombinant full length human CB2 receptor expressed in HEK293 cell membranes after 90 mins by topcount scintillatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed